Forcing the application to run under administrative privileges and legacy conditions resolves basic permissions issues.
For Alice: Madness Returns , the original release suffered from several notorious technical oversights. The most common issues that a crackfix or manual configuration patch addresses include: Alice Madness Returns Crackfix SKIDROW
The crack alone often isn't enough to make the game run smoothly on modern systems. Consider these manual adjustments: Alice Madness Returns Crackfix SKIDROW