During this era, Naruto was at the absolute peak of its global popularity. The Naruto Shippuden anime adaptation had just begun airing in early 2007. This narrative shift updated the characters' ages, designs, and powers, sparking an unprecedented wave of fan art, fiction, and independent doujinshi. Circles like Naruho-dou used these events to distribute physical copies of their parody works directly to fans. Tsunade as a Focal Point in Fan Works
One day, a mysterious and potent poison began to spread throughout the village, infecting many of its residents. The villagers, afflicted with excruciating pain and crippling symptoms, flocked to Tsunade's clinic in desperation. As the village's top medical expert, Tsunade took it upon herself to find an antidote. -C72- -Naruho-dou -Naruhodo-- Tsunade no Inchiryou -Naruto-